MOBILE, Ala. (AP) — Former U.S. Attorney General Jeff Sessions lost the Republican nomination for his old Senate seat in Alabama to former college football coach Tommy Tuberville, likely ending a long political career with a bitter defeat egged on by President Donald Trump.

Tuberville, 65, beat Sessions in Tuesday’s Republican runoff as Sessions fell short in his attempted comeback for a seat he held for two decades before resigning to become Trump’s attorney general in 2017.

Familiar to Alabamians from his decade as Auburn University’s head football coach, Tuberville is now positioned for a robust challenge against Democratic U.S. Sen. Doug Jones. With Alabama’s strong GOP tilt, the seat is widely viewed as Republicans’ best chance for a pickup as they try to maintain their thin Senate majority amid Trump’s lagging popularity nationally.

Sessions, 73, was wounded by Trump’s criticisms after he recused himself in the investigation into Russian interference in the 2016 presidential campaign. Sessions, who’d been the first U.S. senator to endorse Trump during the GOP presidential primary campaign, insisted he was required by law to recuse because he was a potential subject and witness given his campaign ties to the president.